Gene name:
Npffr2 (Gpr74;Npff2;Npgpr) ;
Protein name:
Neuropeptide FF receptor 2 ;
Alternative:
Neuropeptide G-protein coupled receptor ;G-protein coupled receptor 74 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGKRWDSNSS | GSWDHIWSGN | DTQHPWYSDI | NITYMNYYLH | QPHVTAVFIS |
100:
SYFLIFFLCM | VGNTVVCFVV | IRNRYMHTVT | NFFIFNLAIS | DLLVGIFCMP |
150:
ITLLDNIIAG | WPFGSSMCKI | SGLVQGISVA | ASVFTLVAIA | VDRFRCVVYP |
200:
FKPKLTVKTA | FVMIVIIWGL | AITIMTPSAI | MLHVQEEKYY | RVRLSSHNKT |
250:
STVYWCREDW | PNQEMRRIYT | TVLFATIYLA | PLSLIVIMYA | RIGASLFKTS |
300:
AHSTGKQRLE | QWHVSKKKQK | VIKMLLTVAL | LFILSWLPLW | TLMMLSDYAD |
350:
LSPNKLRVIN | IYVYPFAHWL | AFCNSSVNPI | IYGFFNENFR | SGFQDAFQFC |
400:
QKKVKPQEAY | GLRAKRNLDI | NTSGLLVHEP | ASQNPSGENL | GCRKSADNPT |
417:
QESLMEETGE | ATNSTET
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Rat Neuropeptide FF receptor 2
ELISA Kit for Rat Neuropeptide FF receptor 2
ELISA Kit for Rat Neuropeptide FF receptor 2
CLIA Kit for Rat Neuropeptide FF receptor 2
CLIA Kit for Rat Neuropeptide FF receptor 2
CLIA Kit for Rat Neuropeptide FF receptor 2
Polyclonal Antibody for Rat Neuropeptide FF receptor 2
Polyclonal Antibody for Rat Neuropeptide FF receptor 2
Polyclonal Antibody for Rat Neuropeptide FF receptor 2
Monoclonal Antibody for Rat Neuropeptide FF receptor 2
Monoclonal Antibody for Rat Neuropeptide FF receptor 2
Monoclonal Antibody for Rat Neuropeptide FF receptor 2
Protein for Rat Neuropeptide FF receptor 2
Protein for Rat Neuropeptide FF receptor 2
Protein for Rat Neuropeptide FF receptor 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Identification and characterization of two G protein-coupled receptors for neuropeptide FF."
Bonini J.A.
,
Jones K.A.
,
Adham N.
,
Forray C.
,
Artymyshyn R.
,
Durkin M.M.
,
Smith K.E.
,
Tamm J.A.
,
Boteju L.W.
,
Lakhlani P.P.
,
Raddatz R.
,
Yao W.-J.
,
Ogozalek K.L.
,
Boyle N.
,
Kouranova E.V.
,
Quan Y.
,
Vaysse P.J.
,
Wetzel J.M.
,
Branchek T.A.
,
Gerald C.
,
Borowsky B.
more...
J. Biol. Chem.275:39324-39331(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .